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Friday, November 14, 2008
Targeting Of 5-HT1A Receptors, Journal Of Neuroscience
Depression is associated with decreased binding of serotonin 5 HT1A receptors. Receptors must be targeted to the appropriate membrane domain function properly, and although trafficking mechanisms have been elucidated for some receptors, little is known about how serotonin receptors are targeted to dendrites. Because the C terminus of 5 HT1A receptors is required for targeting, Carrel et al.